Publications by authors named "L Ortigosa"

Celiac disease is strongly associated with HLA DQ, specifically with haplotypes. DRB1*03-DQA1*05:01/DQB1*02:01 (DQ2.5),DRB1*07-DQA1*02:01/DQB1*02:02 (DQ2.

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Objectives: The objective of this study was to assess the association between serological markers and changes of the intestinal mucosa in children with celiac disease (CD).

Methods: Clinical data from CD patients under 15 years old were collected from the participating centers in an on-line multicenter nationwide observational Spanish registry called REPAC-2 (2011-2017). Correlation between anti-tissue transglutaminase antibodies (t-TGA) levels and other variables, including mucosal damage and clinical findings (symptoms, age, and gender), was assessed.

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Brazil ranked second in the world for the number of aesthetic procedures carried out in 2019. Five case reports of delayed hypersensitivity reaction to hyaluronic acid dermal filler after COVID-19 vaccination are presented in this paper. Additional vaccination for new variants, including omicron, will be necessary; therefore, aesthetic professionals should be aware of this possibility and advise patients accordingly.

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Background: Treatment for coeliac disease is a lifelong strict gluten-free diet. Although guidelines recommend regular follow-up with dietary interviews and coeliac serology, these methods may be inaccurate.

Aim: To evaluate the usefulness of faecal gluten immunogenic peptides to support the diagnosis and to determine the adherence to the gluten-free diet in coeliac children.

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Article Synopsis
  • - Celiac disease (CD) is an immune disorder driven by genetic and environmental factors, particularly influenced by the intestinal microbiota, which may contribute to gluten intolerance in at-risk individuals.
  • - A study involving 127 infants with a family history of CD found that formula feeding was associated with higher levels of certain harmful bacteria, specifically Clostridium perfringens and Clostridium difficile, compared to breastfed infants.
  • - The research highlighted that infants' genetic risk for CD affected the presence of enterotoxigenic E. coli in their microbiota, particularly in those who were breastfed or formula-fed, indicating that feeding practices and genetic predispositions play roles in microbiome composition and potentially CD risk.
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