Publications by authors named "L Orozco-Covarrubias"
Background: Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare, usually fatal complication of blood transfusion.
Objective: To describe the characteristics of TA-GVHD in children.
Methods: The clinical records of pediatric patients diagnosed with TA-GVHD between January 2007 and December 2021 were reviewed.
Article Synopsis
- - Ecthyma gangrenosum (EG) is a skin condition mainly caused by Pseudomonas aeruginosa infections in immunocompromised patients, presenting with reddish-purple spots that can progress quickly to severe skin ulcers.
- - A study analyzed 17 EG patients, revealing that many had underlying conditions like acute lymphoblastic leukemia; most presented with systemic symptoms like fever and pain, and P. aeruginosa was the most commonly isolated bacteria.
- - The findings suggest that if a patient shows fever and pain with rapidly worsening skin lesions, physicians should suspect EG and start treatment without waiting for lab results.
The human skin harbors a wide variety of microbes that, together with their genetic information and host interactions, form the human skin microbiome. The role of the human microbiome in the development of various diseases has lately gained interest. According to several studies, changes in the cutaneous microbiota are involved in the pathophysiology of several dermatoses.
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