At 40 years of the 'Golden Chain'. Which are the stem cells in ectocervical epithelium?

In normal vaginal and ectocervical epithelium there is no consistent drop in density of the cytoplasmic ultrastructure at the transition between basal cells and parabasal cells. A peculiar golden-brownish argyrophilia, limited to the basal cells and vanishing in dysplasias, had been imputed to this density [2]. The reproducibility of the pertinent silver stain was improved.

Tackling the non-linearizeable dose-response relationship in clotting time assays of heparin.

Heparin sodium was assayed by turbidimetric measurement of the clotting time of bovine citrate plasma with thromboplastin, between the moment of recalcification and the moment of maximal speed of polymerization of the fibrinogen monomer, as marked by the turning-point of the trace of the turbidimetric record. Most assays were practiced in the range of 0.2-2.

[Prevention of false results in tests for occult blood in feces].

The HaemoQuant test and the immunological tests are not devoid of problems so that the (pseudo)peroxidase-sensitive tests are anything but obsolete. Most of the tests are nowadays sold with reduced sensitivity, with the risk of false-negative results. Nevertheless, they can yield false-positive results without a strict dairy-and-vegetable diet in which all components have undergone a heat inactivation (cooking, baking, pasteurization).

Simple monitoring of low salicylate concentrations in capillary blood. An appraisal of ultraviolet spectrophotometric methods.

The differential ultraviolet spectrophotometric determination of salicylate according to Williams et al. (11) and the single extraction ultraviolet spectrophotometric method of Stevenson (9) are subject to interference by serotonin. Probably as a result of this interference, the results are erratic when low concentrations of salicylate are monitored in capillary blood.