Na-MRI as a Noninvasive Biomarker for Cancer Diagnosis and Prognosis.

The influx of sodium (Na ) ions into a resting cell is regulated by Na channels and by Na /H and Na /Ca exchangers, whereas Na ion efflux is mediated by the activity of Na /K -ATPase to maintain a high transmembrane Na ion gradient. Dysfunction of this system leads to changes in the intracellular sodium concentration that promotes cancer metastasis by mediating invasion and migration. In addition, the accumulation of extracellular Na ions in cancer due to inflammation contributes to tumor immunogenicity.

Characterization of low power research reactor neutrons for the validation of k(0)-INAA standardization based on k(0)-IAEA software.

Channel Bsite2 of Ghana research reactor-1 has been characterized for k0-INAA application. Cadmium ratio and bare multi-monitor were used to determine flux parameters using 0.1%Au-Al, Fe, and Zr wire as flux monitors.