Publications by authors named "L O Ingram"
Article Synopsis
- Static stretching is commonly used to improve flexibility, but there's no clear consensus on the best way to do it in terms of frequency, intensity, or volume.
- A systematic review of 189 studies with over 6,600 adults found that both acute and chronic static stretching significantly increased flexibility, with chronic stretching showing a larger effect.
- The research indicated that factors like age, sex, and training status did not significantly influence flexibility outcomes, although those with poor initial flexibility saw greater improvements compared to those with average flexibility.
Article Synopsis
- The review aimed to evaluate how effective community-based allied health services are in reducing the need for acute care, while also gathering the perspectives of stakeholders involved.
- A total of 67 studies were analyzed, focusing on various allied health professions and assessing methodological quality using established appraisal tools.
- The findings showed mixed results about the effectiveness of these services, with patients generally having positive experiences, but the certainty of evidence for significant outcomes was deemed "very low," suggesting that results should be interpreted cautiously.
Article Synopsis
- Warm water temperatures contribute to recurrent mass mortality in farmed Pacific oysters, but the causes behind initial outbreaks (index cases) remain unclear.
- Environmental comparisons of four index cases in Australia (2010, 2013, 2016, and 2024) revealed low rainfall and significant temperature changes prior to the outbreaks, increasing oyster vulnerability.
- While no clear patterns in seawater or air temperatures were found, the presence of harmful algae and potential new viral strains suggest environmental monitoring and research protocols need enhancement to better predict future events.
Background: Pegfilgrastim is a long-acting recombinant human granulocyte colony-stimulating factor biologic that is indicated to reduce the incidence of infections, manifested by febrile neutropenia, in patients receiving myelosuppressive anti-cancer drugs and to increase survival in patients acutely exposed to myelosuppressive doses of radiation. Due to the high cost of biologic therapy and the scarcity of biosimilar alternatives, there is an unmet medical need for targeted biologics.
Objective: This comparative analytical investigation aimed to confirm the similarity of biosimilar Stimufend® (pegfilgrastim-fpgk) to reference product Neulasta® (pegfilgrastim).