Publications by authors named "L Nogowski"
Ostarine does not enhance the metabolic effect of exercise in obese rats.
J Physiol Pharmacol
August 2023
Overweight and obesity are associated with severe metabolic disorders and an increased risk of cardiovascular diseases. It is a known fact that physical activity has a positive effect on metabolic parameters, and also reduces the risk of diseases such as diabetes. Some products can enhance the rate of lipolysis and help in improving fat loss.
View Article and Find Full Text PDFOstarine is the most popular compound in the selective androgen receptor modulator group (SARMs). Ostarine is used as a physical performance-enhancing agent. The abuse of this agent in higher doses may lead to severe side effects.
View Article and Find Full Text PDFOstarine (also known as enobosarm or Gtx-024) belongs to the selective androgen receptor modulators (SARMs). It is a substance with an aryl-propionamide structure, classified as a non-steroidal compound that is not subjected to the typical steroid transformations of aromatization and reduction by α5 reductase. Despite ongoing research on ostarine, knowledge about it is still limited.
View Article and Find Full Text PDFArticle Synopsis
- This study investigates spexin as a potential blood marker during the transition period in dairy cows, exploring its relationship with various biochemical metabolites and hormones.
- Spexin levels decrease leading up to calving, with the lowest concentrations observed on calving day, followed by a rise during the first two weeks of lactation, indicating an important change in the transition process.
- The research finds correlations between spexin and other metabolites, specifically a negative correlation with nonesterified fatty acids and total ghrelin, while showing a positive relationship with progesterone levels, suggesting spexin’s involvement in dairy cow metabolism and health during this critical period.
Objective: Kisspeptin (KP) is a major regulator of reproductive functions. It has also been shown to be involved in the metabolic changes associated with obesity. According to the well-established concept of prenatal programming, environmental factors can influence physiological and behavioral systems at the early stages of development.
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