Publications by authors named "L Njim"

Article Synopsis
  • - The study examines the health benefits of extra virgin olive oil (EVOO) combined with diallyl sulfide (DAS) in diabetic mice, focusing on its anti-diabetic and protective effects on various organs.
  • - EVOO significantly reduced elevated glucose and liver enzyme levels while normalizing harmful lipids, and it also improved the antioxidant defenses of the mice by enhancing key enzymes.
  • - The findings suggest that the combination of EVOO and DAS has strong potential as functional foods for managing diabetes and its related complications.
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Gastrointestinal clear cell sarcoma (GICCS)/malignant gastrointestinal neuroectodermal tumor (GNET) is an extremely rare form of cancer with aggressive clinical behavior. It has distinct pathological, immunohistochemical, ultrastructural, and molecular features. Herein, we present the case of a 20-year-old woman with no notable medical history who presented to the outpatient department with complaints of abdominal pain and vomiting.

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Article Synopsis
  • * This study explores thymoquinone (TQ), derived from black seeds, as a potential cancer treatment by encapsulating it in lipid nanocapsules (LNCs), enhancing its delivery and absorption.
  • * Results show that TQ-LNCs effectively reduced tumor size in mice more than free TQ, suggesting that this method could improve CRC treatment outcomes with fewer side effects.
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Post-traumatic fibro-osseous lesions (PTFOL) are a rare and benign tumor that typically affects the ribs and is probably caused by an excessive post-traumatic reactive process. PTFOL primarily affects the sixth, seventh, and eighth ribs. Here, we report a case of a PTFOL with an unusual location and expansion that simulated a malignant chest tumor.

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Ultrapure silicon nanoparticles (SiNPs) produced by femtosecond laser ablation in water have attracted great interest in the area of cancer therapy as they are efficient as photosensitizers in photodynamic therapy modality and can induce cell hyperthermia under radiofrequency radiation. Recently, we showed that these biocompatible nanoparticles were not able to reach tumors after intravenous injection in mice due to their rapid clearance from the bloodstream. In order to increase their half-life time and therefore their chances to reach and accumulate in tumors by an enhanced permeation retention (EPR) effect, a capping agent on SiNP surface acting as a colloidal stabilizer suspension is required.

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