Intracerebral grafting of dopamine-producing cells is proposed as a strategy to replace the typical neurons lost to Parkinson's disease (PD) and improve the typical PD motor symptoms. Non-human primate studies have provided clues on the relationship between host's immune response and grafting success. Herein, we discuss how the host's immune system differentially affects the graft depending on the origin of the cells and reflect on the advantages and limitations of the immune paradigms utilized to assess graft-related outcomes.
View Article and Find Full Text PDFSleep Restriction Therapy (SRT) is a core component of cognitive behavioural therapy for insomnia (CBT-I). Yet, adherence to SRT can be a major challenge for patients. As this challenge is evident in conventional face-to-face therapy, it raises the question of adherence to SRT in internet-delivered therapy.
View Article and Find Full Text PDFSchool Nursing Evidence-Based Clinical Practice Guideline for Students with Seizures and Epilepsy School Nursing Evidence-Based Clinical Practice Guideline: Students with Seizures and Epilepsy CPG Implementation Toolkit.
View Article and Find Full Text PDFGynecol Obstet Fertil Senol
January 2025
Background: The CAMDEX-DS is an instrument to diagnose Alzheimer's disease (AD) in Down syndrome consisting of an informant interview and a cognitive test battery (CAMCOG-DS). Measurement properties of the German CAMDEX-DS were investigated.
Method: Fifty-five adults with Down syndrome (19-58 years) participated in this observational study.