Publications by authors named "L Naseralallah"
Background Diabetic nephropathy is a serious complication of diabetes that significantly increases the risk of chronic kidney disease (CKD) and end-stage renal disease (ESRD). A critical concern in managing patients with diabetic nephropathy is the prevalence of potentially inappropriate medications (PIMs), which can exacerbate kidney dysfunction and lead to adverse health outcomes. PIMs are defined as medications whose risks outweigh their benefits, particularly when safer alternatives are available.
View Article and Find Full Text PDFBackground: Heparin and its derivates, including unfractionated heparin (UFH) and low molecular weight heparin (LMWH), are among the most commonly used anticoagulants. Nonetheless, their use has been associated with hyperkalemia.
Objective: To determine and compare the incidence, magnitude, and potential risk factors of hyperkalemia in patients receiving UFH versus LMWH in a real-world clinical setting.
Article Synopsis
- - Depression is common among stroke survivors, and SSRIs like escitalopram and sertraline are often prescribed, but they can cause low sodium levels (hyponatremia), which may worsen patient outcomes.
- - This study reviewed hospital records from 401 patients over five years to compare the incidence and severity of hyponatremia in those treated with either escitalopram or sertraline.
- - Results showed that both medications were linked to an increased risk of mild hyponatremia, with no significant differences in outcomes between the two drugs, highlighting the need for caution when prescribing these SSRIs.
Aprocitentan: a new emerging prospect in the pharmacotherapy of hypertension.
Blood Press
December 2024
Background: Resistant hypertension (RH) is linked to higher risks of cardiovascular events and there remains an unmet therapeutic need driven by pathophysiologic pathways unaddressed by guideline-recommended therapy. Whilst spironolactone is considered the preferred fourth-line therapy, its broad application is limited by its safety profile. Aprocitentan is a novel dual endothelin (ET) A and B receptors antagonist that has been recently approved by the FDA.
View Article and Find Full Text PDFPurpose: To provide an insight into the role of a clinical pharmacy initiative in a surgical urology unit through evaluating the nature, significance, associated medications, and acceptance rate of pharmacist interventions.
Methods: A cross-sectional study was carried out at the Ambulatory Care Center (ACC), Doha, Qatar. Data related to clinical pharmacist interventions and associated rationale were classified according to the nature of the intervention using an adapted classification system.