Case Report: A rare case of familial lung cancer requiring pneumonectomy in three male siblings.

Lung cancer is a disease with a unique genetic pattern and is occasionally related to hereditary syndromes such as Lynch, Louis-Bar, and Li-Fraumeni. In some patients, germinal mutations may be discovered in combination with somatic alterations. For instance, Li-Fraumeni syndrome often reveals a mixture of and mutations.

Case of Hereditary Papillary Renal Cell Carcinoma Type I in a Patient With a Germline Mutation in Russia.

Hereditary papillary renal carcinoma (HPRC) is a rare autosomal dominant disease characterized by the development of multiple papillary type I renal cell carcinomas. This hereditary kidney cancer form is caused by activating mutations in . Descriptions of patients with HPRC are scarce in the world literature, and no cases have been described in open sources in Russia.

Melanoma arising in a Giant congenital melanocytic nevus: two case reports.

Background: A giant congenital melanocytic nevus (GCMN) is found in 0.1% of live-born infants. If present, the lesion has a chance of about 6% to develop into malignant melanoma.