[INTERACTION OF BETA-BLOCKER PROPRANOLOL WITH RENIN-ANGIOTENSIN SYSTEM INHIBITORS IN RAT KIDNEY].

Propranolol injection (0.5 mg/kg, s.c.

[Interaction of renin-angiotensin system inhibitors with dopamine in rat kidney].

Dopamine (1 mg/kg, s.c.) causes 2.

[Analysis of the role of neurohumoral systems in action of dopaminomimetic dopamine on ion-regulating renal function].

Dopamine causes in anesthetized rats expressed diuretic response that is accompanied by an increase in GRF and a significant enhance of sodium and potassium excretion. Pretreatment the animals in diclofenac sodium or contrical in doses, that inhibit respectively activity of renal PG-system and kallikrein-kinin system, don't prevent of renal effects of dopamine. Preliminary assignment a direct renin inhibitor aliskiren enhances the diuretic, natriuretic and kaliyuretic effects of the drug.