Synthesis and physico-chemical investigation of thiolated dextran derivative: Design and application of a redox-responsive drug delivery system.

In the present investigation, redox-responsive-based dextran carriers were developed for the controlled release of hydrophobic molecules via a reducing agent naturally present in cells, namely glutathione. In this sense, dextran was modified with a thiol derivative. The roles of the hydrophilic segments in the molecular self-organisation of polysaccharide derivatives into nanoparticles were investigated by varying the average dextran molar mass.

Hidden Factors of Limited Time and Busyness: A Qualitative, Multicentre Study of the Reasons for Missed Nursing Care.

Aim: To explore nurses' perceptions of reasons for missed nursing care.

Design: A multicentre qualitative descriptive study was undertaken from August 2022 to January 2023.

Methods: Interpretive description methodology was used.

Reduced healthcare costs for patients with screen-detected colorectal cancer: A Danish nationwide cohort study.

Objectives: This Danish nationwide retrospective register-based cohort study investigated healthcare costs for patients with screen-detected colorectal cancer (SD-CRC) compared to non-screen-detected CRC (NSD-CRC).

Study Design: Nationwide cohort study.

Methods: Quarterly healthcare costs including costs of hospital care, out-of-hospital medication, and primary sector contacts were compared between the two groups from two years before diagnosis of CRC until two years after.

Associations between number and type of conditions and physical activity levels in adults with multimorbidity - a cross-sectional study from the Danish Lolland-Falster health study.

Aim: To provide detailed descriptions of the amount of daily physical activity (PA) performed by people with multimorbidity and investigate the association between the number of conditions, multimorbidity profiles, and PA.

Methods: All adults (≥18 years) from The Lolland-Falster Health Study, conducted from 2016 to 2020, who had PA measured with accelerometers and reported medical conditions were included (n=2,158). Sedentary behavior and daily PA at light, moderate, vigorous, and moderate to vigorous intensity and number of steps were measured with two accelerometers.

Measurement of non-invasive rectal and ear temperature in inpatients ≥ 18 years old: A cross-sectional comparative study.

Introduction: Body temperature measurement is a fundamental requirement for clinical decisions in nursing care, medical diagnosis, and treatment. Therefore, it is pivotal that body temperature measurements are accurate and precise.

Aims: To test the diagnostic accuracy of an ear temperature screening procedure among adult hospitalized patients.