Publications by authors named "L N Gall"
Glial-vascular interactions are critical for the formation and maintenance of brain blood vessels and the blood-brain barrier (BBB) in mammals, but their role in the zebrafish BBB remains unclear. Using three glial gene promoters-, , and (a truncated )-we explored glial-vascular development in zebrafish. Sparse labeling showed fewer glial-vascular interactions at early stages, with glial coverage and contact area increasing with age.
View Article and Find Full Text PDFBackground: Emergency appendicectomy (EA) is a common procedure, yet few studies have focused on gender differences in these patients. This study aims to evaluate the demographics, preoperative investigations, intraoperative findings, and clinical outcomes between males and females undergoing EA.
Methods: A multicenter retrospective observational study was conducted across four hospitals involving patients who underwent EA between August 2018 and November 2025.
Article Synopsis
- Coral reefs are severely degraded due to human activities, prompting restoration efforts to improve coral cover and fish communities.
- In a study on Little Cayman Island, researchers found that after 85 days of coral restoration, there were no significant changes in fish biomass, abundance, or species richness.
- The findings suggest that coral restoration may have limited effects on fish populations in well-protected areas, highlighting the need for future programs to consider local ecology and the complex interactions between fish and corals.
Article Synopsis
- Brown seaweeds are vital to coastal ecosystems, but they are threatened by climate change, prompting a detailed genetic study.
- The research traced the evolutionary history of brown algae, highlighting significant gene families and metabolic pathways related to their adaptation and functional diversity.
- Findings also indicated that the integration of large viral genomes has played a crucial role in shaping the genetics and traits of brown algal species over time.
Article Synopsis
- DUX4 is the main gene linked to facioscapulohumeral dystrophy (FSHD), with effective mouse models, such as ACTA1-MCM/FLExDUX4, being used for research.
- The study focused on observing muscle changes in tibialis anterior and quadriceps at various stages, confirming the presence of progressive muscular dystrophy and identifying issues related to tamoxifen use and gene selection for DUX4 assessment.
- A new functional test was created to assess muscle strength, which revealed that DUX4 expression leads to weaker muscles with lower initial force but maintained power and endurance, suggesting potential applications for this model in human clinical evaluations.