[Efficiency of antibiotics in children with acute respiratory infection complicated by pneumonia dependent on the acetylation type in the Far North regions].

Clinical characteristics of some diseases are defined by the phenotype of metabolic reactions, for example N-acetylation. Genetic polymorphism due to the activity of N-acetyltransferase (N-AT) is common in the majority of human populations. Consequently, persons with "slow" or "fast" acetylation phenotype should be identified.

[Viral and bacterial associations and their role in the development of bronchopulmonary diseases in children].

Clinical and laboratory criteria for estimating the role of viruses and bacteria that determine bronchopulmonary diseases have been derived. The clinical importance of the detectable microflora, part of which permanently invade the nasopharynx (pneumococcus, adenoviruses) is under critical review. Pneumonias that may develop within the first days of acute respiratory viral infection are characterized by monoviral influenzal or RS-infection; later pneumonias are marked by viral infection with the predominance of adenoviruses.

[Genotypic differences in the level of N-acetyltransferase activity in mice of inbred lines and their hybrids].

There are "slow" and "rapid" acetylator phenotypes in mice according to N-acetyltransferase activity (E.C. 2.

[Determination of the phenotype of N-acetyltransferase activity].

The authors suggest a simple easily reproducible micromethod for determination of genetically determined activity of N-acetyltransferase (EC 2.3.1.