[Chemoradiotherapy in the combined treatment for laryngopharyngeal cancer].

The study included 62 patients with morphologically verified squamous cell carcinoma of laryngopharynx, stages T2-4N0-2M0. As a result of the treatment complete regression was recorded in 28.1 ± 7.

[Restoration of the vocal function in the patients with laryngeal cancer after organ-saving surgery].

The objective of the present study was to enhance the effectiveness of vocal rehabilitation and to improve the quality of life in the patients presenting with laryngeal cancer after organ-preserving surgical interventions. The study included 98 patients presenting with stage II-III laryngeal cancer who underwent organ-preserving surgery and postoperative vocal rehabilitation. The comprehensive approach to the restoration of the vocal function has been developed and clinically applied that includes rational psychotherapy, respiratory gymnastics for the correction of physiological and phonation breathing, activation of the neuromuscular apparatus of the external and the residual internal larynx and neck muscles , coordination of the vocal apparatus at the expense of compensation of the remaining part of the larynx taking advantage of the biological feedback mechanism based on the results of mathematical simulation.

[Quality of life in laryngectomized patients after vocal rehabilitation].

The study included patients with laryngeal cancer (stage III-IV) after laryngectomy. They underwent vocal rehabilitation assisted by biological monitoring using mathematical modeling and computer technology. EORTS QLQ-C30 questionnaires 30 (version 3.

[A medical hardware complex for speech signal research in patients with phonation disorders].

The main elements of a medical hardware complex for speech signal research in patients with phonation disorders are considered. The complex is based on a model of human auditory system. It is shown that the complex can be used for speech recovery and diagnosis of the state of speech production apparatus.

[Combined treatment of patients with oral tumors with extracorporeal neutron-photon therapy].

Combined therapy with preoperative course of remote neutron therapy was given to 29 patients with oral cavity cancer. All the patients had stage III of morphologically verified squamous cell carcinoma. Partial tumor regression after radiotherapy was observed in 39.