Study on groundwater pollution and its human impact analysis using geospatial techniques in semi-urban of south India.

Groundwater recharging and thus renewable groundwater supplies will experience considerable changes due to climate change. The present investigation focussed to evaluate the susceptibility of subsurface water in rapid developing textile industrial region of Southern India. To determine the aquifer's susceptibility, the DRASTIC-LU Remote sensing and GIS based vulnerability model was applied and the results were compared with human activity risk (HAR) analysis to ensure the water borne disease on human health.

Distinct molecular features of FLNC mutations, associated with different clinical phenotypes.

Filamin С is a key an actin-binding protein of muscle cells playing a critical role in maintaining structural integrity and sarcomere organization. FLNC mutations contribute to various types of cardiomyopathies and myopathies through potentially different molecular mechanisms. Here, we described the impact of two clinically distinct FLNC variants (R1267Q associated with arrhythmogenic cardiomyopathy and V2264M associated with restrictive cardiomyopathy) on calcium homeostasis, electrophysiology, and gene expression profile of iPSC-derived patient-specific cardiomyocytes.

Mindfulness training for cardiovascular health in type 2 diabetes: A critical review.

Mindfulness training has gained increasing attention as a potential intervention to improve cardiovascular health, particularly in populations with chronic conditions, such as type 2 diabetes. Given the heightened cardiovascular risk associated with type 2 diabetes, identifying effective non-pharmacological strategies to mitigate these risks is crucial. This critical review assessed the current evidence on the impact of mindfulness training on cardiovascular health in individuals with type 2 diabetes.