Publications by authors named "L Muthami"

Background: People living with diabetes can reduce their risk of vision loss from diabetic retinopathy by attending screening, which enables early detection and timely treatment. The aim of this pilot trial was to assess the feasibility of a full-scale cluster randomized controlled trial of an intervention to increase uptake of retinal examination in this population, as delivered within existing community-based diabetes support groups (DSGs).

Methods: All 16 DSGs in Kirinyaga county were invited to participate in the study.

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Background: There is limited evidence on how implementation of peer support interventions influences effectiveness, particularly for individuals with diabetes. We conducted a cluster randomized controlled trial to compare the effectiveness of a peer-led health education package versus usual care to increase uptake of screening for diabetic retinopathy (DR).

Methods: Our process evaluation used a mixed-method design to investigate the recruitment and retention, reach, dose, fidelity, acceptability, and context of implementation, and was guided by the Consolidated Framework for Implementation Research (CFIR).

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Article Synopsis
  • - The study examined the effectiveness of unattended automated office blood pressure (uAOBP) in screening for hypertension among a sample of 982 Kenyan adults, using 24-hour ambulatory blood pressure monitoring as a benchmark.
  • - Results indicated that while the average systolic BP readings from uAOBP were similar to those from 24-hour monitoring, there was wide variability and a notable drop in sensitivity as the blood pressure cutoffs increased from ≥130/80 mmHg to ≥140/90 mmHg.
  • - It was found that uAOBP was more accurate in detecting hypertension in overweight and obese individuals, highlighting the need for improved screening methods, as significant misclassification occurred in the general population.
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Background: All patients with diabetes are at risk of developing diabetic retinopathy (DR), a progressive and potentially blinding condition. Early treatment of DR prevents visual impairment and blindness. The natural history of DR is that it is asymptomatic until the advanced stages, thus annual retinal examination is recommended for early detection.

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Background: The use of clinical practice guidelines envisages augmenting quality and best practice in clinical outcomes. Generic guidelines that are not adapted for local use often fail to produce these outcomes. Adaptation is a systematic and rigorous process that should maintain the quality and validity of the guideline, while making it more usable by the targeted users.

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