Publications by authors named "L Mora Rios"
The high plasticity of cells undergoing epithelial-mesenchymal transition (EMT) promotes increased tumor heterogeneity, and its interaction with tumor-associated stromal cells appears to contribute to developing a stemness phenotype. Cells with these characteristics exhibit increased resistance to chemotherapy and radiotherapy, leading to disease relapse and metastasis. Here, we discuss the activation of the Wnt/β-catenin pathway in promoting EMT and stemness within the context of cellular resistance to these therapies.
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- Elevated levels of fasting plasma total homocysteine (tHcy) and a specific genetic variant (methylenetetrahydrofolate reductase C677T polymorphism) are linked to hypertension, but the role of the l-Arginine pathway was previously unclear.
- A study involving 788 adults found that higher tHcy levels were positively related to two metabolites (ADMA and SDMA) and negatively associated with the l-Arginine/ADMA ratio, indicating a potential protective effect against hypertension.
- The analysis suggested that both tHcy and ADMA play intermediary roles in how the genetic variant affects hypertension risk, highlighting the importance of the l-Arginine pathway in this relationship.
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- Gentiana lutea rhizomes are notable for their bitter taste and are explored for uses in phytotherapy, animal nutrition, food processing, cosmetics, and agroecology.
- A study analyzed the biochemical composition of 55 rhizomes from four French mountain regions (Alpes, Jura, Massif Central, and Pyrénées) using various analytical methods including NIRS, fluorescence, and HS-SPME-GCMS.
- The findings indicate that using data fusion strategies can effectively differentiate the geographical origin of Gentiana lutea roots, suggesting these methods may enhance quality assessments compared to using individual analytical techniques; however, environmental factors must also be considered for accurate origin determination within a single massif.
Background: Cancer is the fourth leading cause of death in adolescents and young adults (AYA) worldwide. Although successful treatment of cancer in AYA has increased in recent years in most of the world, this is not true for many low- and middle-income countries (LMIC) where over 80% of all AYA live. This study investigated the needs of AYA with cancer in parts of Latin America (LATAM) through the perspectives of non-physician health care providers and partners.
View Article and Find Full Text PDFThis work discusses the health promotion challenges of men who have sex with men (MSM) through the use of data from a conversation circle with people from institutions that provide services to MSM in the Metropolitan Region of Recife. The results allow for the identification of the following challenges for health promotion work, not only for MSM but also for sex dissidents: difficulties with the use of identity categories, stigmatization for providing them with sexual health care, structural racism, the deprivation of liberty, extreme poverty, and literacy.
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