Publications by authors named "L Mongioi'"

Article Synopsis
  • Varicocele affects up to 15% of men and is linked to infertility; various surgical and radiological methods exist for treatment, but their effectiveness is uncertain.
  • A study comparing the Ivanissevich surgical technique and sclerotherapy in 94 patients found that sclerotherapy significantly improved sperm concentration, while surgical treatment reduced the number of patients with oligozoospermia.
  • Overall, the study did not determine a clear advantage of one method over the other but highlighted the importance of considering sperm bio-functional parameters in future research.
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Article Synopsis
  • The role of specific sperm RNAs in idiopathic male infertility is not well understood, particularly in distinguishing between infertile and fertile men.
  • There are observable differences in non-coding RNA expressions related to spermatogenesis, which may impact embryo quality and the success of sperm retrieval in azoospermic patients.
  • Further research with larger sample sizes is needed to explore cost-effective RNA panels, which could guide infertility management and therapeutic strategies.
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Varicocele is a prevalent condition in the infertile male population. However, to date, which patients may benefit most from varicocele repair is still a matter of debate. The purpose of this study was to evaluate whether certain preintervention sperm parameters are predictive of successful varicocele repair, defined as an improvement in total motile sperm count (TMSC).

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Varicocele has a prevalence of 15% in the population and represents a primary cause of infertility in 40% of cases and a secondary cause in approximately 80% of cases. It is considered the major correctable cause of male infertility. Despite its high prevalence in the infertile population, a large number of patients with varicocele do not experience reproductive difficulties.

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Background: This single-center real-life study was conducted to evaluate the most effective combination of nutraceuticals and the most appropriate indications for the treatment of male infertile patients.

Methods: Infertile patients aged 20-55 years were treated with a combination of antioxidants (Androlen; Enfarma, Misterbianco, Catania, Italy) (group A), with Androlen (Enfarma) and a mixture of fibrinolytic molecules (Lenidase, Enfarma) (group B), or Androlen (Enfarma) and other molecules different from those used for the patients of the group B (group C). Patients were also subdivided according to the presence of varicocele, mild testicular hypotrophy, idiopathic infertility, and chronic male accessory gland infection.

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