Publications by authors named "L Molteni"

Article Synopsis
  • Cenobamate (CNB) is a newly approved antiseizure medication for adults with focal-onset seizures who haven’t responded to at least two other treatments, but it may interact with other drugs requiring careful monitoring.
  • This study presents an innovative method using Volumetric Absorptive Microsampling (VAMS) for accurately measuring CNB levels in patients, validated according to rigorous guidelines.
  • The results show the new method is reliable, with strong accuracy and precision, and stable for up to 15 days, making it a promising option for therapeutic drug monitoring in CNB treatment.
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Aims: To assess the effects of IDegLira on glucometric indices deriving from intermittently scanned Continuous Glucose Monitoring (isCGM) in patients with type 2 diabetes (T2D).

Methods: Retrospective, observational, cohort, multi-center, "pre - post" study. All adults consecutively identified in the medical records who started treatment with IDegLira, and for whom an isCGM report before and after the initiation of IDegLira was available were included in the study.

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Background: Blinding is thought to minimise expectancy effects and biases in double-blind randomised-controlled trials (RCTs). However, whether blinding integrity should be assessed and reported remains debated. Furthermore, it is unknown whether blinding failure influences the outcome of RCTs in anxiety disorders.

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Objective: People with mental illness are overrepresented throughout the criminal justice system. In Italy, the Judicial Psychiatric Hospitals are now on the edge of their closure in favor of small-scale therapeutic facilities (REMS). Therefore, when patients end their duty for criminal behaviors, their clinical management moves back to the outpatient psychiatric centers.

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Interoception is defined as the sense of the internal state of the body. Dysfunctions in interoception are found in several mental disorders, including trauma-related conditions. Mindfulness-Based Interventions (MBIs) have been shown to influence interoceptive processes.

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