Publications by authors named "L Mohanty"
Article Synopsis
- Bone neoplasms are a group of tumors that mainly affect the appendicular skeleton, especially in adolescents and young adults, and pose significant health risks due to their rapid growth and potential for metastasis.
- This retrospective study examined 63 patients at a medical college in Western India over 18 months, focusing on age, sex distribution, and tumor types based on WHO classification, finding a mean patient age of 25.8 years and a male-to-female ratio of 1.17:1.
- The study revealed that benign tumors were more common (57.11%) than malignant ones (42.85%), with giant cell tumors and osteosarcoma being the most frequently identified types respectively.
Background: Attempts should be made to identify the molecule-based biomarkers, which give indication about the progression of precancer and malignancy of the oral area.
Aim: To evaluate the reliability of methylation of genes of saliva like P16, MGMT, and DAP-K as biomarkers for diagnosis of oral squamous cell carcinoma.
Methods And Materials: This study included 30 cases of histopathologically proven cases of oral squamous cell carcinoma.
Background: The process of curing and regaining the integrity of damaged tissues is known as healing. An autologous concentration of platelets embedded in plasma is known as platelet-rich plasma (PRP).
Aim: This study was conducted to evaluate the role of PRP in the fast healing of wounds and complications in oral surgical procedures.
Article Synopsis
- Genomic methylation shows promise as a tool for identifying oral potentially malignant disorders (OPMDS) and oral cancer, which could enhance understanding of cancer mechanisms and lead to new therapies.
- A study involving 112 patients with premalignant and malignant oral lesions analyzed saliva samples to investigate genetic markers like p16, DAP-K, and MGMT using advanced DNA methylation technology.
- Findings indicated that 12.7% of oral cancer lesions displayed methylation of the examined genes, with higher rates of co-methylation, suggesting these genetic markers can aid in predicting the progression of oral cancer and patient outcomes.
Background: Although congenital ureteropelvic junction (UPJ) obstruction is the most common cause of neonatal hydronephrosis, aetiopathogenesis is still inconclusive. Recently, the paucity of interstitial cells of Cajal (ICC) at the narrow adynamic part of UPJ has been implicated as a causative factor.
Materials And Methods: This prospective study was conducted between October 2019 and March 2022 to find out the density of ICC by the immunohistochemical method using CD117 (c-kit) antibody, in resected segments of UPJ in obstruction patients and in renal tumour patients as control.