Publications by authors named "L Miguel-Escuder"
Objective: To review the clinical utility of endoretinal biopsies in diagnostically undefined cases of vitreoretinal lymphoma (VRL) with negative vitreous cytology.
Methods: Retrospective case series including all consecutive patients who underwent endoretinal biopsies in a tertiary care center, Hospital Clinic of Barcelona (Spain), between 2014 and 2020.
Results: A total of 5 patients were included in this study.
Article Synopsis
- Ocular toxoplasmosis (OT), caused by the Toxoplasma gondii parasite, is the leading cause of posterior uveitis globally, which can lead to visual impairment and blindness.
- A systematic review and meta-analysis of 72 studies identified various factors influencing recurrences and visual impairment in OT patients, focusing on clinical, environmental, parasite, host, and treatment-related factors.
- The analysis included 4,200 patients, revealing a recurrence rate of 49%, notably higher in South America compared to Europe.
Cystoid macular edema (CME) is the most common cause of decreased visual acuity after both vitrectomy and cataract surgery. Various strategies have been used for its treatment, such as intravitreal corticosteroids. The intravitreal fluocinolone acetonide implant (Iluvien) is approved for the treatment of persisting diabetic macular edema and for the prevention of recurrence of non-infectious uveitis affecting the posterior segment.
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- Anti-TNF-α-induced lupus (ATIL) is a rare form of drug-induced lupus that can occur in patients undergoing anti-TNF-α therapy, particularly those with non-infectious uveitis (NIU).
- The study presents three cases of patients who developed symptoms like positive antinuclear antibodies (ANA), arthritis, and skin lesions after starting adalimumab, which resolved upon withdrawal of the medication.
- The findings suggest common characteristics among these cases, such as the onset of symptoms linked to anti-TNF-α treatment and a review of existing literature supports their classification within ATIL.
Purpose: To describe the effectiveness and safety of nicergoline in patients with epithelial corneal defect or corneal ulcer due to neurotrophic keratitis (NK).
Methods: A prospective case series review was performed in 14 patients with NK who started treatment with nicergoline as an off-label prescription from January to November 2020. Patients with a epithelial defect or corneal ulcer due to NK were treated with oral nicergoline.