Publications by authors named "L Michael Glode"
Article Synopsis
- The study focused on the sexual dysfunction faced by couples after localized prostate cancer treatment and evaluated an online intervention aimed at helping them regain sexual intimacy.
- A randomized controlled trial involved couples who underwent various treatment modalities, with six online modules tailored to their needs and experiences, assessing their outcomes over 3 and 6 months.
- Results showed no significant difference in overall satisfaction about sex life after 6 months, but the intervention group reported increased engagement in sexual activities at 3 months, with many participants expressing satisfaction with the program and recommending it to others.
Background: Activating mutations of the tyrosine kinase receptor KIT have been described in both mastocytosis and gastrointestinal stromal tumors (GIST), but are usually found in separate domains and often respond differently to signal transduction inhibitors. We describe here a large family with both GIST, mastocytosis, and achalasia. Affected family members have a unique activating mutation in exon 9 of KIT which show promise to a novel signal transduction inhibitor.
View Article and Find Full Text PDFBackground: Plant derivatives have been studied as therapies for prostate cancer based on their purported anti-inflammatory and antioxidant properties and low toxicities. The acai berry is an example of a plant rich in phytochemicals, which may slow the growth of prostate cancer.
Methods: This was a phase II, Simon 2-stage clinical trial in patients with biochemically recurrent prostate cancer with a primary endpoint of prostate-specific antigen (PSA) response.