Publications by authors named "L Metz"
Article Synopsis
- * Researchers used a technique involving sulfonate functionalized N-heterocyclic carbene (NHC) Ir complexes and a special structural framework called a G-sphere to create these nanoclusters through hydrogen reduction.
- * The resulting nanoclusters (1.8 ± 0.4 nm) exhibited a narrow size distribution and were highly effective as catalysts for hydrogenating 4-nitrostyrene, showcasing superior selectivity compared to larger, non-encapsulated Ir clusters.
Background: The integrated care for older people (ICOPE) program, developed by the World Health Organization, serves as a public health initiative to maintain older adults' functional abilities and promote healthier aging. Here, we adapted the ICOPE approach to assess overall prevalence of frailty in rural and semi-urban areas. We also investigated health-related quality of life and physical activity and sedentary behavior in older people.
View Article and Find Full Text PDFIntroduction: The rate of neurodegeneration in multiple sclerosis (MS) is an important biomarker for disease progression but can be challenging to quantify. The brain age gap, which quantifies the difference between a patient's chronological and their estimated biological brain age, might be a valuable biomarker of neurodegeneration in patients with MS. Thus, the aim of this study was to investigate the value of an image-based prediction of the brain age gap using a deep learning model and compare brain age gap values between healthy individuals and patients with MS.
View Article and Find Full Text PDFGrotte Mandrin is located in the middle Rhône River Valley, in Mediterranean France, and has yielded 11 Pleistocene archeological and paleoanthropological layers (ranging from the oldest layer J to the youngest layer B) dating from Marine Isotope Stage (MIS) 5 to MIS 3. We report here the nearly complete dentition of an adult Neanderthal individual, nicknamed 'Thorin,' associated to the last phase of the Post-Neronian II, in layer B2 (∼44.50-42.
View Article and Find Full Text PDFBackground: Disease progression is observed across the spectrum of people with multiple sclerosis (MS) and identification of effective treatment strategies to halt progression remains one of the greatest unmet clinical needs.
Objectives: The Canadian Prospective Cohort Study to Understand Progression in MS (CanProCo) was designed to evaluate a wide range of factors associated with the onset and rate of clinical disease progression in MS and to describe the interplay between these factors.
Design: A prospective cohort study.