Publications by authors named "L Metsch"

Background: Black women living with HIV (WLHIV) often have suboptimal ART adherence due to a multitude of social and structural barriers, including HIV-related stigma. Trust in healthcare providers plays a significant role in adhering to ART and is likely lower among Black WLHIV compared to their White counterparts. This study examined the relationship between experienced stigma in healthcare settings and ART adherence and viral suppression through anticipated stigma in healthcare settings, internalized stigma, and medical mistrust.

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Background: There is high post-hospital discharge mortality among persons with HIV who are hospitalized, and post-hospital survival is strongly associated with early HIV clinic linkage, clinic attendance, and antiretroviral therapy adherence. The Daraja intervention, a context-tailored case management strategy implemented and tested through a randomized trial in Tanzania, was associated with improved HIV clinic linkage, retention, and ART initiation and adherence.

Methods: We conducted in-depth interviews (IDIs) in a sub-sample of 40 study participants (20 control and 20 intervention) 12 months after enrollment into the trial to gain an in-depth understanding of the barriers to HIV care engagement and the perceived mechanisms through which the Daraja intervention impacted these barriers.

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To determine whether endorsement patterns of psychosocial symptoms revealed distinct subgroups, or latent classes, of people living with HIV who use substances (PLWH-SU), and to assess whether these classes demonstrated differential health outcomes over time. This study uses data from 801 PLWH-SU initially enrolled across 11 US hospitals during 2012-2014 and followed up in 2017. Latent class analysis included 28 psychosocial items.

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Article Synopsis
  • The study focuses on a Comprehensive-TeleHarm Reduction (C-THR) intervention aimed at improving HIV prevention services for people who inject drugs (PWID) through syringe services programs (SSP) in Miami, Florida.
  • The CHARIOT trial will involve 350 PWID participants who will be randomly assigned to receive either C-THR or standard clinic referrals, with the goal of increasing engagement in HIV prevention methods like PrEP and medications for opioid use disorder.
  • The outcomes will be assessed over 12 months, focusing on factors such as engagement, effectiveness, cost-effectiveness, and barriers to implementing the C-THR intervention.
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Importance: Despite the widespread availability of antiretroviral therapy (ART), people with HIV still experience high mortality after hospital admission.

Objective: To determine whether a linkage case management intervention (named "Daraja" ["bridge" in Kiswahili]) that was designed to address barriers to HIV care engagement could improve posthospital outcomes.

Design, Setting, And Participants: Single-blind, individually randomized clinical trial to evaluate the effectiveness of the Daraja intervention.

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