Publications by authors named "L McKee"

Objective: The present study assessed two theory-driven mediators of the effects of a family group cognitive-behavioral (FGCB) preventive intervention for youth of parents with a history of major depressive disorder (MDD) or dysthymia on long-term youth psychopathology symptoms and diagnoses.

Method: Sample included 180 parents ( = 41.9, 89% female, 82% White, non-Hispanic) and one of their children/adolescents ages 9-15 years ( = 11.

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A 45 % drug loaded (DL) amorphous nanoparticle (ANP) formulation for a BCS IV drug demonstrated promising pharmacokinetics in dogs (Purohit, et al., J. Pharm.

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Article Synopsis
  • - The study focuses on how proper regulation of communication between cells is essential for the differentiation of cells in plants, particularly in *Arabidopsis thaliana*.
  • - Researchers analyzed gene expression in surrounding somatic and germline cells and found that β-1,3-glucan, a polysaccharide, plays a significant role in cell insulation and signaling through channels called plasmodesmata.
  • - The presence of β-1,3-glucanase in the female germline disrupted this insulation, allowing for changes that affected gene expression and ultimately halted germline development, indicating its crucial role in successful female gamete formation.
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Article Synopsis
  • * The study focuses on CBM family 92, which specifically binds to β-1,6-glucans while showing diversity in the enzymes associated with it.
  • * The research includes crystal structures of two CBM92 proteins and identifies key tryptophan residues that aid in ligand binding, suggesting potential applications for these proteins in linking polysaccharides and enzyme immobilization.
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The evaluation of plant-based feedstocks is an important aspect of biorefining. Nicotiana glauca is a solanaceous, non-food crop that produces large amounts of biomass and is well adapted to grow in suboptimal conditions. In the present article, compatible sequential solvent extractions were applied to N.

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