Multiplex Evaluation of Biointerface-Targeting Abilities and Affinity of Synthetized Nanoparticles-A Step Towards Improved Nanoplatforms for Biomedical Applications.

To obtain versatile nanoplatforms comparable for various bio-applications, synthesis and functionalization of two inorganic nanoparticles (NPs), i.e., gold (AuNPs) and iron oxide (SPIONs), are described for different NP diameters.

Lentisk () Oil Nanoemulsions Loaded with Levofloxacin: Phytochemical Profiles and Antibiofilm Activity against spp.

Most clinical isolates of both and show the capacity to adhere to abiotic surfaces and to develop biofilms resulting in a contribution to chronic human skin infections. Antibiotic resistance and poor biofilm penetration are the main causes of ineffective therapeutic treatment in killing bacteria within biofilms. A possible strategy could be represented by drug delivery systems, such as nanoemulsions (composed of bioactive oil, surfactant and water phase), which are useful for enhancing the drug permeation of a loaded drug inside the biofilm and its activity.

Every breath you take: High concentration of breathable microplastics in indoor environments.

The widespread presence of microplastics (MPs) in the air and their potential impact on human health underscore the pressing need to develop robust methods for quantifying their presence, particularly in the breathable fraction (<5 μm). In this study, Raman micro-spectroscopy (μRaman) was employed to assess the concentration of indoor airborne MPs >1 μm in four indoor environments (a meeting room, a workshop, and two apartments) under different levels of human activity. The indoor airborne MP concentration spanned between 58 and 684 MPs per cubic meter (MP m) (median 212 MP m, MPs/non-plastic ratio 0-1.

Peptides with Antimicrobial Activity in the Saliva of the Malaria Vector .

Mosquito saliva plays a crucial physiological role in both sugar and blood feeding by helping sugar digestion and exerting antihemostatic functions. During meal acquisition, mosquitoes are exposed to the internalization of external microbes. Since mosquitoes reingest significant amounts of saliva during feeding, we hypothesized that salivary antimicrobial components may participate in the protection of mouthparts, the crop, and the gut by inhibiting bacterial growth.

Gentamicin loaded niosomes against intracellular uropathogenic Escherichia coli strains.

Urinary tract infections (UTIs) are the most common bacterial infections and uropathogenic Escherichia coli (UPEC) is the main etiological agent of UTIs. UPEC can persist in bladder cells protected by immunological defenses and antibiotics and intracellular behavior leads to difficulty in eradicating the infection. The aim of this paper is to design, prepare and characterize surfactant-based nanocarriers (niosomes) able to entrap antimicrobial drug and potentially to delivery and release antibiotics into UPEC-infected cells.