[Modulatory effect of glucans on the function of murine macrophages, NK-cells and lymphocytes].

The particulate glucan (G1), soluble glucan preparations (G2 to G5, and G7) isolated from Saccharomyces cerevisiae, and glucomanan prepared from culture fluid after cultivation of Candida utilis (G6) were tested for their immunomodulatory activity in vivo and in vitro. In tests in vivo three soluble glucans (G3, G4, and G7) injected s.c.

[Structure and various characteristics of yeast beta-D-glucans].

Yeast cell wall contains mainly polysaccharides. Among them beta-1,3-D-glucans play role of the skeletal carcass of the yeast cell wall, while D-mannans represent its surface antigens. Mannans are built of alpha-1,6-linked polymannosyl backbone with the side chains consisting of alpha-1,2- and alpha-1,3-linked mannosyl units.

Immunochemical and structural analysis of the cell wall mannan as the basis of the taxonomic reidentification of a yeast strain.

The immunochemical properties and structural features of D-mannans from two Candida parapsilosis strains were studied. Weak cross-reactivity of D-mannans with antisera produced to C. parapsilosis strains was observed, as well as significant differences in the mannans structures were found by means of methylation analysis, acetolysis and 1H-NMR spectroscopy.

Novel structure of the cellular mannan of the pathogenic yeast Candida krusei.

On the basis of methylation analysis, 13C- and 1H-n.m.r.