Performances of preoperative CT scan to predict the pTN stage for MSI/dMMR localized colon cancers.

Background: Neoadjuvant immunotherapy emerges as a promising strategy for patients with localized colon cancer (CC) harboring microsatellite instability/mismatch repair deficiency (MSI/dMMR). The aim of this study is to evaluate the concordance between clinical cTN stage assessed by preoperative computed tomography (CT) scan and pTN stage of MSI/dMMR CC.

Patients And Methods: Consecutive patients diagnosed for localized MSI/dMMR CC and treated with upfront surgery between 2013 and 2022 in two French centers were eligible.

Nationwide trends over 10 years in epidemiology and management of pancreatic ductal adenocarcinoma: A real-world study from the French administrative database.

Background & Aims: Significant progress has been made in the management of pancreatic ductal adenocarcinoma (PDAC) in recent years. In this population-based study, we aimed to compare incidence, therapeutic strategies, and survival outcomes of PDAC patients in France over a decade.

Methods: This study was performed using a nationwide French database.

[Acute renal failure in a patient undergoing oncological treatment].

With the increasing prevalence of neoplasia and kidney disease, patients undergoing oncological treatment are at greater risk of acute renal failure. Joint oncological and nephrological management requires a thorough understanding of the patient's clinical history, as well as the potential nephrotoxic effects of chemotherapy and immunotherapy. This article proposes a comprehensive approach to the assessment of acute renal failure in patients undergoing treatment for neoplasia.

The Relevance of Communication Between Alzheimer's Patients and Their Caregivers. Effective Prosody Strategies to Improve Communication.

One of the most critical factors in Alzheimer's disease (AD) is communication between patients and caregivers. A relevant part of the way of speaking is what is known as prosody, or the variations a speaker makes when talking. To our knowledge, no research has analyzed the relevance of communication for caregivers when speaking with AD patients or what they consider the most effective strategies to communicate with them.