Publications by authors named "L Marziani"

Introduction: Knee osteotomy combined with meniscal allograft transplantation (MAT) showed promising results to treat unicompartmental knee osteoarthritis (OA) secondary to meniscal deficiency and knee malalignment. However, there is still no high-level evidence to demonstrate whether the combination of these two treatments is superior to osteotomy alone.

Methods And Analysis: 52 patients with unicompartmental knee OA Kellgren-Lawrence grade ≤3 secondary to meniscal deficiency and knee malalignment (aged 20-60 years) are randomised to undergo knee osteotomy associated with MAT or knee osteotomy alone in a 1:1 ratio.

View Article and Find Full Text PDF

Purpose: This study aim was to analyze the joint temperature of patients affected by bilateral knee osteoarthritis (OA) using infrared thermography to investigate whether thermographic imaging patterns are influenced by the severity of symptoms and joint degeneration.

Methods: Sixty-sixpatients ranging from 43 to 78 years old (63.3 ± 8.

View Article and Find Full Text PDF

Background: Platelet-rich plasma (PRP) is one of the most frequently used orthobiologic products for the injection treatment of patients affected by knee osteoarthritis (OA). Some preliminary evidence supports the influence of platelet concentration on patients' clinical outcomes.

Purpose: To analyze if platelet concentration can influence the safety and clinical efficacy of PRP injections for the treatment of patients with knee OA.

View Article and Find Full Text PDF

Purpose: The aim of this study was to evaluate if the operated knee environment remains abnormal in patients successfully treated with anterior cruciate ligament reconstruction (ACL-R).

Methods: Thirty asymptomatic patients were enrolled (28 men, 2 women, age 28.6 ± 6.

View Article and Find Full Text PDF
Article Synopsis
  • - A study was conducted on 203 patients to evaluate the effectiveness of a cell-free osteochondral scaffold for treating knee cartilage lesions, focusing on how patient and lesion characteristics impact outcomes.
  • - Results showed significant improvements in patients' knee function and activity levels over 24 months, although some experienced mild (39.0%) or severe (1.5%) adverse reactions, and a small failure rate (2.0% to 12.3% including clinical failures).
  • - Factors such as age, gender, type of lesion, and previous surgeries were linked to differences in recovery, with better outcomes observed in patients with osteochondritis dissecans compared to degenerative lesions.
View Article and Find Full Text PDF