Publications by authors named "L Martinez Pineiro"

Article Synopsis
  • Lymphogranuloma venereum (LGV) is a sexually transmitted infection primarily affecting men who have sex with men (MSM), with significant prevalence in HIV-positive individuals and proctitis as a common symptom.
  • A study was conducted to analyze the genetic characteristics of LGV isolates from six hospitals in Spain using multilocus sequence typing (MLST) and other genetic methods.
  • Results showed that a majority of isolates were L2 genotypes, with L2-ST53 and L2-ST58 being the most common profiles, indicating complex transmission networks and potential co-circulation of different strains.
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Development of multicellular organisms requires well-orchestrated interplay between cell-intrinsic transcription factors and cell-cell signaling. One set of highly conserved transcription factors that plays diverse roles in development is the SoxC group. contains a sole SoxC protein, SEM-2.

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Article Synopsis
  • Enterovirus D68 (EV-D68) infections can cause severe respiratory issues and acute flaccid myelitis, with a significant rise reported during the fall-winter season of 2021-2022 across Europe.
  • The study by the European Non-Polio Enterovirus Network (ENPEN) analyzed over 10,481 samples from 19 countries, identifying 1,004 as EV-D68, predominantly affecting young children, where 37.9% required hospitalization.
  • Additionally, genetic analyses uncovered two new B3-derived lineages without regional patterns, indicating a notable impact of the infections and the emergence of new virus strains.
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Persistent cytopenia in the post-hematopoietic cell transplantation (HCT) setting can occur despite adequate engraftment of donor cells. PLX-R18, a placental-derived mesenchymal-like cell product, is expanded ex vivo in a 3-dimensional environment. PLX-R18 cells secrete a large array of hematopoietic factors, which promote regeneration, maturation, and differentiation of hematopoietic cells and stimulate their migration to peripheral blood.

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