Publications by authors named "L Marthong"
Stomach cancer is the fifth most common cancer in terms of prevalence and incidence and the fourth leading cause of mortality in men and women worldwide. It is well-established that aberrant DNA methylation in cells can lead to carcinogenesis. The primary objective of our study was to investigate the aberrant DNA methylation status of genes associated with stomach cancer with a particular reference to the ethnic population of Mizoram, North East India.
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- - Oropharyngeal cancer, common in Meghalaya, India, is linked to unique risks like smokeless tobacco and areca nut consumption, but its underlying genetic changes are not well understood.
- - This study analyzed DNA methylation and gene expression in oropharyngeal cancer patients, finding 194 silenced and 241 overexpressed genes, with key pathways related to immune responses and osteoclast differentiation significantly involved.
- - The research showed differences in DNA methylation and gene expression compared to other head and neck cancers, and no HPV DNA was found in the tumor samples, enhancing the understanding of oropharyngeal cancer.