Publications by authors named "L Marchetta"
Article Synopsis
- Risk-reducing salpingo-oophorectomy (RRSO) is recommended for women with BRCA1/2 pathogenic variants to prevent ovarian cancer, but many still refuse the surgery despite its benefits.
- A study at a referral center in Italy analyzed 287 women, finding a high uptake rate of 96.1% for RRSO after counseling, although some women were hesitant due to fears about menopause and childbearing.
- The study suggests that a specialized clinic with a supportive team and options for surveillance plays a crucial role in encouraging women to consider risk-reducing surgery.
Background: Granulosa cell tumors (GCTs) are rare neoplasia that account for less than 5 % of all the ovarian tumors. Juvenile GCT histotype is generally observed in adolescent and young women, representing a very rare disease, so only a paucity of data are present in literature. The aim of this study is to analyse the oncologic and fertility outcome in our case series of juvenile GCTs.
View Article and Find Full Text PDFObjective: Immature teratomas are rare malignant ovarian germ cell tumours, typically diagnosed in young women, where fertility-sparing surgery is the treatment of choice. The role of adjuvant chemotherapy in stage I disease remains controversial. We evaluated the impact of surveillance versus chemotherapy on the recurrence rate in stage I immature teratomas.
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- The study investigates the 2022 monkeypox outbreak, examining its epidemiology, clinical features, and virology through a retrospective analysis in a Dermatology unit involving 124 subjects.
- The majority of participants were men, with a high percentage living with HIV, and the disease predominantly spread through sexual contact; symptoms included a vesicular rash and systemic issues, most commonly proctitis.
- The findings highlight the importance of early detection in at-risk populations and the efficacy of lesion swab samples for diagnosing the disease, with a high survival rate noted among patients.
This study in healthy subjects examined the effects of a system delivering focal microvibrations at high frequency (Equistasi®) on tonic vibration stimulus (TVS)-induced inhibition of the soleus muscle H reflex. Highfrequency microvibrations significantly increased the inhibitory effect of TVS on the H reflex for up to three minutes. Moreover, Equistasi® also significantly reduced alpha-motoneuron excitability, as indicated by the changes in the ratio between the maximumamplitude H reflex (Hmax reflex) and the maximumamplitude muscle response (Mmax response); this effect was due to reduction of the amplitude of the H reflex because the amplitude of muscle response remained unchanged.
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