Chronic stress situations lead to an impairment of immune response and higher oxidative and inflammatory stress, which are important underlying mechanisms of the ageing process. However, given that the physiological stress response depends on the subjective appraisal of a given stressor, the aim of the study was to investigate the effect that different degrees of perceived stress have, regardless of their type, on immune functions, oxidative and inflammatory stress and ageing rate of women (30-50 years old). For that purpose, a group of 49 women was classified, according to their scores obtained in the perceived stress scale (PSS), into low (n = 23), moderate (n = 14) and high (n = 12) degree of perceived stress.
View Article and Find Full Text PDFOxidative stress plays an essential and early role in the pathophysiology of Alzheimer's disease (AD). Alterations in the redox state in AD and in mild cognitive impairment (MCI) patients appear in the brain and at peripheral level. Given that it is easier to study the latter, most of the research has been focused on plasma.
View Article and Find Full Text PDFChild labor is a complex problem that violates the fundamental rights of children and affects their psychophysical development. Child labor affects 215 million children in the world and 115 million perform activities defined as the "worst forms of child labor". Most child labor is in agriculture (60%), where the majority are unpaid family workers, compared to 26% in services and 7% in industry.
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