Publications by authors named "L Manenti"
Article Synopsis
- The XENONnT dark matter experiment successfully measured nuclear recoils from solar ^{8}B neutrinos, marking a significant advancement in neutrino detection technology.
- Using a two-phase time projection chamber with a 5.9 t liquid xenon target, the experiment produced 37 observed events, which surpassed the expected background events, indicating a notable signal.
- The results provide a measured solar neutrino flux consistent with previous studies and confirm the neutrino cross section predictions aligned with the Standard Model, showcasing the effectiveness of dark matter detectors in neutrino research.
Background: Chronic kidney disease (CKD)-associated pruritus is a condition that strongly impacts CKD patients and is associated with increased morbidity/mortality, and worse health-related quality of life (HRQoL). Difelikefalin is currently the only drug approved in Europe specifically for treating moderate to severe CKD-associated pruritus in patients undergoing hemodialysis. The KALM-1 and KALM-2 trials showed better efficacy of difelikefalin vs placebo and best supportive care.
View Article and Find Full Text PDFThe multi-staged XENON program at INFN Laboratori Nazionali del Gran Sasso aims to detect dark matter with two-phase liquid xenon time projection chambers of increasing size and sensitivity. The XENONnT experiment is the latest detector in the program, planned to be an upgrade of its predecessor XENON1T. It features an active target of 5.
View Article and Find Full Text PDFIgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. IgAN causes end-stage kidney disease (ESKD) in 30-40% of all cases. The activation of the complement system by pathological circulating IgAs, which is often associated with low serum C3 levels (LowC3), seems to play a crucial role.
View Article and Find Full Text PDF