Publications by authors named "L Malisova"
Article Synopsis
- * A total of 18 carbapenemase variants were identified, predominantly in ST131 clades A and C, with the most common variants being detected in 14 and 12 countries, respectively.
- * The rise in isolates carrying these genes since 2021 highlights a significant public health threat posed by the high-risk ST131 lineage.
Article Synopsis
- * Microscopy techniques confirmed that the bacteria's size increased significantly; short-axis size grew by 28% and long-axis by 54% under antibiotic pressure.
- * Genome sequencing identified several mutations in genes related to cell shape, suggesting that these morphological changes help the bacteria adapt and survive in environments altered by antibiotic treatment.
Article Synopsis
- Aminopenicillins, like ampicillin, are recommended for treating Haemophilus influenzae infections, but resistance can develop through mutations in the ftsI gene affecting penicillin binding protein 3 (PBP3).
- The study aimed to compare how ampicillin and cefuroxime influence mutations in H. influenzae, focusing on the minimum inhibitory concentration and amino acid changes in PBP3 over time.
- Results showed cefuroxime led to a greater increase in minimum inhibitory concentration and different PBP3 mutations compared to ampicillin, indicating varying mutation selection between the two antibiotics.
The objective of this study was to assess the susceptibility of cefiderocol against multidrug-resistant carbapenemase-producing and nonproducing bacteria. The panel comprised 182 isolates of the order , and 40 strains of . Antimicrobial susceptibility testing has been performed using broth microdilution method according to the European Committee on Antimicrobial Susceptibility Testing recommendations.
View Article and Find Full Text PDF[Case report of fatal sepsis caused by Actinobacillus suis/equuli in an adult male].
Klin Mikrobiol Infekc Lek
June 2022
This is a case report of sepsis caused by the species Actinobacillus suis/equuli in a male agriculture worker that ended fatally. The article also contains information on identification and results of antibiotic susceptibility testing. This is a rare case of human infection and probably the first case of a human being infected by this species in the Czech Republic.
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