Publications by authors named "L Maione"
Cushing-induced Male Hypogonadism: Deciphering a Prevalent Yet Understudied Relationship.
J Clin Endocrinol Metab
November 2024
Article Synopsis
- Remission of acromegaly is determined by the normal levels of GH/IGF-1 hormones based on a patient's age and gender.
- Although there is extensive information on treatment methods and the health issues linked to ongoing acromegaly, less is known about how long it takes to achieve remission and its effects.
- The authors highlight findings from the UK acromegaly registry, indicating that how quickly patients reach biochemical remission is a key factor in their overall survival.
Article Synopsis
- * A total of 7,943 adult patients were identified, showing a prevalence of 10.4 cases per 100,000 and an annual incidence of 0.76 per 100,000, with complications such as hypertension, sleep apnea, and diabetes being commonly reported.
- * Findings indicate that diabetes significantly increases the risk for other serious health issues like myocardial infarction and cancer, emphasizing the need for comprehensive treatment approaches which include pituitary surgery and radiotherapy.
Objective: Testosterone concentrations, albeit rarely, may be in the normal range (>3.0 ng/mL) in men with a prolactin-secreting pituitary adenoma (PSPA-nt). The evolution of total, bioavailable testosterone, gonadotropin levels, and that of graded symptoms of testosterone deficiency (TD) are uncertain in these patients.
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