Publications by authors named "L Mahieu"

The English grain aphid, Sitobion avenae, is a significant agricultural pest affecting wheat, barley, and oats. In Chile, the most prevalent and persistent clone (superclone) of S. avenae harbors the facultative endosymbiont bacterium Regiella insecticola.

View Article and Find Full Text PDF

Bacterial pneumonia greatly contributes to the disease burden and mortality of lower respiratory tract infections among all age groups and risk profiles. Therefore, laboratory modelling of bacterial pneumonia remains important for elucidating the complex host-pathogen interactions and to determine drug efficacy and toxicity. In vitro cell culture enables for the creation of high-throughput, specific disease models in a tightly controlled environment.

View Article and Find Full Text PDF
Article Synopsis
  • Developed an AI software system to predict late-onset sepsis (LOS) and necrotizing enterocolitis (NEC) in premature infants in the NICU using continuous monitoring data.
  • The study used an XGBoost machine learning algorithm on a dataset of 865 preterm infants, achieving a sensitivity of 69% for all episodes and 81% for severe cases, significantly reducing the time to diagnosis.
  • The AI model's predictions can support clinicians' early detection efforts, indicating potential clinical and socioeconomic benefits, with further studies needed to understand the combined impact of AI and clinical expertise on patient outcomes.
View Article and Find Full Text PDF

Background: Meticillin-sensitive Staphylococcus aureus (MSSA) infection is a significant health concern in neonatal intensive care units (NICUs). Bacterial colonization increases the risk of subsequent infection, leading to morbidity and mortality.

Aim: To report the findings of a retrospective cohort study on the surveillance of MSSA colonization and infection in NICU patients.

View Article and Find Full Text PDF

Background: Congenital cytomegalovirus infection (cCMV) is the most common congenital infection worldwide and is a major cause of neurodevelopmental impairment in children. At this point there are insufficient data on neurodevelopmental outcome of children with cCMV, both symptomatic and asymptomatic.

Aim: This study aimed to describe the neurodevelopmental outcome in a large prospective cohort of children with cCMV.

View Article and Find Full Text PDF