Publications by authors named "L Maffioli"
Article Synopsis
- The study examined how the immune response in serum and saliva changes after receiving a booster dose of the BNT162b2 vaccine, comparing samples from healthcare workers collected before and after the booster shot.* -
- After the booster, levels of specific antibodies (IgG and IgA) significantly increased in both serum and saliva compared to before the booster, indicating a strong immune response. However, while serum IgG and IgA levels rose significantly, salivary IgG levels were lower and salivary neutralizing activity against variants was notably reduced.* -
- Results showed that although the booster restored serum neutralizing ability against multiple variants of concern (like Delta and Omicron), the salivary neutralization ability was much less effective
We derive the transient-time correlation function (TTCF) expression for the computation of phase variables of inhomogenous confined atomistic fluids undergoing boundary-driven planar shear (Couette) flow at constant pressure. Using nonequilibrium molecular dynamics simulations, we then apply the TTCF formalism to the computation of the shear stress and the slip velocity for atomistic fluids at realistic low shear rates, in systems under constant pressure and constant volume. We show that, compared to direct averaging of multiple trajectories, the TTCF method dramatically improves the accuracy of the results at low shear rates and that it is suitable to investigate the tribology and rheology of atomistically detailed confined fluids at realistic flow rates.
View Article and Find Full Text PDFBackground: Although the BNT162b2 COVID-19 vaccine is known to induce IgG neutralizing antibodies in serum protecting against COVID-19, it has not been studied in detail whether it could generate specific immunity at mucosal sites, which represent the primary route of entry of SARS-CoV-2.
Methods: Samples of serum and saliva of 60 BNT162b2-vaccinated healthcare workers were collected at baseline, two weeks after the first dose and two weeks after the second dose. Anti-S1-protein IgG and IgA total antibodies titres and the presence of neutralizing antibodies against the Receptor Binding Domain in both serum and saliva were measured by quantitative and by competitive ELISA, respectively.
The use of robotics is becoming widespread in healthcare. However, little is known about how robotics can affect the relationship with patients during an emergency or how it impacts clinicians in their organization and work. As a hospital responding to the consequences of the COVID-19 pandemic "ASST dei Sette Laghi" (A7L) in Varese, Italy, had to react quickly to protect its staff from infection while coping with high budgetary pressure as prices of Personal Protection Equipment (PPE) increased rapidly.
View Article and Find Full Text PDF