The clinical diagnosis of dermatophytosis and identification of dermatophytes face challenges due to reliance on culture-based methods. Rapid, cost-effective detection techniques for volatile organic compounds (VOCs) have been developed for other microorganisms, but their application to dermatophytes is limited. This study explores using VOCs as diagnostic markers for dermatophytes.
View Article and Find Full Text PDFIntroduction: Non-contrast computed tomography (CT) and CT angiography are the gold standard in neuroimaging diagnostics in the case of suspected stroke. CT perfusion (CTP) may play an important role in the diagnosis of stroke mimics (SM), but currently, it is not a standard part of the stroke diagnostic procedure. The project is a multicentre prospective observational clinical research focused on refining the diagnostics of stroke and stroke mimics (SM) in hospital care.
View Article and Find Full Text PDFIschemic stroke is a leading cause of mortality and morbidity worldwide. The time from stroke onset to treatment impacts clinical outcome. Here, we examined whether changing a triage model from "drip and ship" to "mothership" yielded significant reductions of onset-to-groin time (OGT) in patients receiving EVT and onset-to-needle time (ONT) in IVT-treated patients, compared to before FAST-PLUS test implementation.
View Article and Find Full Text PDFA series of waterborne polycarbonate-based poly(urethane-urea) nanocomposite films were prepared and characterized. An isocyanate excess of 30 mol% with respect to the hydroxyl groups was used in the procedure, omitting the chain-extension step of the acetone process in the dispersion preparation. The individual steps of the synthesis of the poly(urethane-urea) matrix were followed by nuclear magnetic resonance (NMR) spectroscopy.
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