[Impairments of co2-gas-exchange during the provocative inhalation in children with bronchial asthma (author's transl)].

Report on the investigation of CO2-Gas-exchange during provocative inhalation tests in children suffering from bronchial asthma. An increased difference in CO2-gradients by increase of PVCO2 and decrease of PACO2 was found. The values of Pco2a are unchanged.

Action of atropine on histamine-induced bronchoconstriction in asthmatic children. A pharmacocapnographic study.

In their earlier methodological model studies the authors confirmed the protective effect of atropine in inhalative acetylcholine provocation. In the present work the role of parasympatholysis is investigated in histamine-induced bronchospasm by the method. It was found that a protective effect was exerted in histamine provocation repeated 20 minutes after subcutaneous administration of atropine sulphate in a dose of 0.

Experiments on placental circulation and transplacental transfer in exteriorized foetuses in hypoxia and after asphyxia in guinea pigs.

Experiments were carried out on near term pregnant guinea pigs. Cesarean section was performed and by exteriorization of the foetuses the placental stage of labor was simulated. In one group of foetuses, chosen at random, we induced hypoxia, and in an another series of experiments asphyxia, each group with its own control.

Altered response in vitro of the human umbilical artery to sera of neonates with respiratory distress syndrome and other hypoxic conditions.

A study was made of the reaction of the human umbilical artery and the isolated rabbit auricular artery to protein-free ultrafiltrates of normal and hypoxic sera originating from neonates suffering from RDS or other acute metabolic disturbances. While a normal serum ultrafiltrate caused an enhanced contraction of the umbilical artery, hypoxic sera exerted a weaker pressor activity. At the same time, on the rabbit's isolated auricular artery the hypoxic sera exhibited a higher pressor activity.