Publications by authors named "L M van den Toorn"
Therapies for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) include balloon pulmonary angioplasty (BPA) and PH-specific medical therapy. This study compares survival and its predictors before and after the introduction of BPA. BPA was independently associated with survival; however, there was no difference in overall survival between the two cohorts.
View Article and Find Full Text PDFObjectives: Interleukin (IL)-6 inhibitors are administered to treat patients hospitalized with COVID-19. In 2021, due to shortages, different dosing regimens of tocilizumab, and a switch to sarilumab, were consecutively implemented. Using real-world data, we compare the effectiveness of these IL-6 inhibitors.
View Article and Find Full Text PDFArticle Synopsis
- The study assesses the survival rates of pulmonary arterial hypertension (PAH) patients over 15 years, analyzing 293 adults diagnosed between 2005 and 2019.
- The findings reveal that while therapeutic advances have been made, overall transplant-free survival rates (median 6.2 years) did not improve significantly over time, particularly for younger patients.
- Factors such as demographic changes and delays in diagnosis may contribute to the stagnant survival rates despite more treatment options being available.
Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19.
Int J Infect Dis
September 2022
Objectives: SARS-CoV-2 Omicron variants BA.1 and BA.2 seem to show reduced clinical severity compared with earlier variants.
View Article and Find Full Text PDF