sRNA113 regulates motility to affect immune response against infection in pearl gentian grouper.

Small RNAs (sRNAs) are a class of molecules capable of perceiving environmental changes and exerting post-transcriptional regulation over target gene expression, thereby influencing bacterial virulence and host immune responses. is a pathogenic bacterium that poses a significant threat to aquatic animal health. However, the regulatory mechanisms of sRNAs in .

[Analysis of 41 cases of myocardial infarction in children with coronary artery lesion after Kawasaki disease].

To analyze the clinical characteristics,diagnosis and treatment of pediatric myocardial infarction (MI) patients with coronary artery lesions (CAL) after Kawasaki disease (KD). Clinical data including baseline characteristics, KD and CAL information, clinical symptoms at MI onset, electrocardiogram (ECG) and imaging findings, MI treatment, and clinical outcomes of 41 MI patients with CAL after KD admitted to the Children's Hospital of Fudan University from January 2017 to August 2024 were analyzed retrospectively. (1) Demographic characteristics: a total of 41 patients were included (36 males and 5 females).

Characterization of a 4'-O-rhamnosyltransferase and de novo biosynthesis of bioactive steroidal triglycosides from Paris polyphylla.

Steroidal saponins in Paris polyphylla featuring complicated sugar chains exhibit notable biological activities, but the sugar chain biosynthesis is still not fully understood. Here, we identified a 4'-O-rhamnosyltransferase (UGT73DY2) from P. polyphylla, which catalyzes the 4'-O-rhamnosylation of polyphyllins V and VI, producing dioscin and pennogenin 3-O-β-chacotrioside, respectively.

The Longitudinal Relationship between Adolescents' Prosocial Behavior and Well-Being: A Cross-Lagged Panel Network Analysis.

Despite extensive research on the relationship between adolescents' prosocial behavior and well-being, few studies have examined the relationships between prosocial acts towards different targets (family, friends, and strangers) and both hedonic and eudaimonic well-being over time, especially within the cultural context of China, where relational closeness are highly emphasized. To address this research gap, the present study conducted a longitudinal investigation involving 514 Chinese adolescents (M = 13.75 years, SD = 1.

A generative adversarial network with multiscale and attention mechanisms for underwater image enhancement.

Underwater images collected are often of low clarity and suffer from severe color distortion due to the marine environment and Illumination conditions. This directly impacts tasks such as marine ecological monitoring and underwater target detection, which rely on image processing. Therefore, enhancing Underwater images to improve their quality is necessary.