[Genetico-demographic patterns of the prevalence of various forms of endogenous psychoses].

Prevalence rates (PRs) for EFP (schizophrenic, schizoaffective and affective psychoses), with allowance for proband sex and age-of-onset data were studied in a subdivided population from the North-East of the European Region of the USSR. The population includes three subpopulations: a small old religious semi-isolate of Russians ("Rs"), aboriginal Komi people ("Ks")--an ethnic community of Ugro-Finnish lineage, and a mixed group of migrants ("Ms") from various regions of the USSR. The latter is mainly an urban population, while the "Rs" and "Ks" are, on the whole, rural populations.

[Dynamics of the epidemiological characteristics of registered contingents of schizophrenia patients].

Different populations of schizophrenic patients under this study were registered by three of the Moscow city outpatient psychiatric departments in 1967, 1975 and 1981. These populations' epidemiologic characteristics compared, the following could be concluded: (1) the specific quantity of patients with psychotic disorders diminished, (2) the percentage of aged patients diminished, (3) the mean observation term reduced. Some other characteristics of the tendency to worsen the medical assistance to psychiatric patients were demonstrated.

[Epidemiologic aspect of the problem of the disability of schizophrenic patients (incidence, chronogenic dynamics, risk factors)].

Epidemiological aspects of disability have been studied in a random sample of schizophrenics living in three Moscow districts. It has been found that 39.4% of schizophrenic patients (44.

[Clinico-demographic characteristics and features of the social and occupational adaptation of schizophrenics in 3 population groups living in the northeastern region of the European portion of the USSR (clinico-epidemiologic study)].

The authors conducted a clinico-epidemiological study of schizophrenics among the indigenous population, including that living in isolated areas and newcomers, taking into consideration forms of the disease course and employing a uniform syndromal assessment of the mental state. The authors have established general pathogenetic regularities of the course and their relationship with the age and sex. Patients from the indigenous population, particularly of geographically isolated areas, showed a higher incidence of schizophrenia, a more severe clinical picture of the disease and a lower level of social and occupational adaptation as compared to the migrated population.

[Population patterns in the development and course of endogenous psychoses as a reflection of their pathogenesis].

An analysis of a representative epidemiological sample of patients with endogenic psychoses (schizophrenia and MDP) revealed statistical distribution of some parameters of the disease (risk of the development of the disease in relation to age, a number of previous attacks, as well as distribution of patients by the duration of paroxysms and remissions). The authors believe that a collation of the tabulated data with the known mathematical models makes it possible to come to understanding some aspects of the pathogenesis of endogenic psychoses.