Tumour content plays a pivotal role in directing the bioinformatic analysis of molecular profiles such as copy number variation (CNV). In clinical application, tumour purity estimation (TPE) is achieved either through visual pathological review [conventional pathology (CP)] or the deconvolution of molecular data. While CP provides a direct measurement, it demonstrates modest reproducibility and lacks standardisation.
View Article and Find Full Text PDFBackground: The lived experience and impact of financial strain on broad physical and mental health outcomes is important and yet underexplored. Improving our depth of understanding of the relationship between financial strain and health may offer important insights to address this complex phenomenon.
Objective: The primary objective of this study was to conduct a meta-synthesis of existing qualitative literature that investigated or described the relationship between financial strain and health outcomes.
Nutr Health
December 2024
Background: Composting is a practical solution to the burgeoning global problem of food waste, which is a significant contributor to landfills and associated environmental effects. Dissemination of accurate information regarding the microbial-driven composting process is critical to positive outcomes.
Aim: To describe the content of news articles addressing composting.
Despite growing attention to other social needs like food and housing insecurity, financial strain, defined as having difficulty making ends meet or lacking money for basic needs, is under-recognized. Inconsistent labels and measures have made the literature difficult to unify. We used many synonyms for financial strain to systematically identify 199 U.
View Article and Find Full Text PDFLinear enamel hypoplasias (LEHs) are development defects appearing as lines or grooves on enamel surfaces. Forming when physiological stressors disrupt developing teeth, LEHs provide retrospective insight into stress experienced in early development. Here, LEHs in Cayo Santiago rhesus macaques (Macaca mulatta) were observed with respect to decade of birth, whether an individual was transferred from the free-ranging colony to the captive facility during probable crown formation periods, and matriline of birth.
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