[Determination of complement in an automatic mode].

A method for the complement determination is suggested by a 50 percent hemolysis microtest with the use of ELISA processor II for automated procedure and registration. The results obtained with this technique virtually do not differ from the data of the routine macromethod. The method is suggested for mass immunologic screenings.

[Relationship between the severity of the course of tetanus poisoning and the resistance level of the macroorganism].

In experiments on rats and rabbits with tetanus poisoning, activation of the nonspecific defence factors (humoral and cellular) was found in the early periods after administration of tetanus toxin. The growth of specific hemagglutinins was recorded later. The survival of the animals was prolonged and the titers of specific antibodies decreased in the course of administering the alpha-adrenoblocker butyroxan.

[Ultrastructural changes in the posterior lobe of the pituitary in tetanus poisoning].

Ultrastructural studies (electron microscopy) of the caudal part of the hypothalamo-hypophysial neurosecretory system were conducted in rats during experimental tetanus. Its activation was found to occur as soon as the initial period after the injection of the toxin, this being apparently connected with the administration of the heterogenous protein, because inactivated toxin proved to induce the same effect. Changes in the vascular permeability, lipid metabolism and the blood coagulation system were also observed.