Identifying risk factors and disease severity in leptospirosis: A meta-analysis of clinical predictors.

Leptospirosis is a bacterial zoonosis with a wide spectrum of clinical presentations. In order to identify potential risk factors and predictors of disease severity, a meta-analysis of the clinical features of severe and non-severe leptospirosis patients was conducted. PubMed was searched to collect studies on the difference in clinical characteristics of severe and nonsevere patients, and data were analyzed using Comprehensive Meta-Analysis V3 software.

ASSOCIATION BETWEEN SERUM ZINC, COPPER AND SELENIUM LEVELS AND THE DEGREE OF LIVER DAMAGE IN PATIENTS WITH CHRONIC HEPATITIS C.

Objective: The aim: To evaluate the content of trace elements Zn, Cu and Se in blood serum and their relationship with viral load and the degree of liver fibrosis according to the results of the FibroMax test in patients with CHC.

Patients And Methods: Materials and methods: 62 outpatients with a verified diagnosis of CHC were under observation, in which serum Zn, Cu and Se levels, viral load and degree of liver fibrosis were determined according to the FibroMax test.

Results: Results: HCV 1b genotype was detected in all patients.

Leptospirosis: Prognostic Model for Patient Mortality in the Transcarpathian Region, Ukraine.

Leptospirosis is a bacterial zoonosis of worldwide distribution with a wide spectrum of clinical presentations that range from subclinical or mild to severe and fatal outcomes. Identifying clinical predictors for the severe form of the disease is critical to reduce disease complications and death. As a result, we conducted a retrospective case-control study to identify clinical markers of mortality in leptospirosis patients from the Transcarpathian region.

[Middle molecular weight peptides from rat blood serum during acute liver injury and administration of iodinated oil].

A spectrum of mean-molecular blood serum peptides in rats with experimental toxic hepatitis and parenteral injection of iodinated oil has been studied using the method of gel-filtration on a sephadex G-25. It is established that the toxic hepatitis is characterized by the expressed rearrangement of the stock of mean-molecular peptides with a preferential growth in the blood serum and normalization of their concentrations 24h after the injection of iodinated oil accompanied by attenuation of the organism intoxication phenomena. An increase in the content of mean-molecular peptides was registered 48 hours after the iodinated oil injection.

[Amino acid reserves of the blood in patients with schizophrenia and their correction in insulin coma].

Free amino acid content was measured in the blood serum in patients with permanently progressive paranoid schizophrenia under conventional insulin shock therapy. The influence of several amino acids (methionine, glutamic acid) preinjection on their base levels was also assessed. Metabolic response to the insulin coma was different in preinjected vs.