Neuronal Population Encoding of Identity in Primate Prefrontal Cortex.

The ventrolateral prefrontal cortex (VLPFC) shows robust activation during the perception of faces and voices. However, little is known about what categorical features of social stimuli drive neural activity in this region. Since perception of identity and expression are critical social functions, we examined whether neural responses to naturalistic stimuli were driven by these two categorical features in the prefrontal cortex.

Multisensory interactions of face and vocal information during perception and memory in ventrolateral prefrontal cortex.

The ventral frontal lobe is a critical node in the circuit that underlies communication, a multisensory process where sensory features of faces and vocalizations come together. The neural basis of face and vocal integration is a topic of great importance since the integration of multiple sensory signals is essential for the decisions that govern our social interactions. Investigations have shown that the macaque ventrolateral prefrontal cortex (VLPFC), a proposed homologue of the human inferior frontal gyrus, is involved in the processing, integration and remembering of audiovisual signals.

Representation of Expression and Identity by Ventral Prefrontal Neurons.

Evidence has suggested that the ventrolateral prefrontal cortex (VLPFC) processes social stimuli, including faces and vocalizations, which are essential for communication. Features embedded within audiovisual stimuli, including emotional expression and caller identity, provide abundant information about an individual's intention, emotional state, motivation, and social status, which are important to encode in a social exchange. However, it is unknown to what extent the VLPFC encodes such features.

Audiovisual integration in macaque face patch neurons.

Primate social communication depends on the perceptual integration of visual and auditory cues, reflected in the multimodal mixing of sensory signals in certain cortical areas. The macaque cortical face patch network, identified through visual, face-selective responses measured with fMRI, is assumed to contribute to visual social interactions. However, whether face patch neurons are also influenced by acoustic information, such as the auditory component of a natural vocalization, remains unknown.