THE ROLE OF ZONULIN IN THE DEVELOPMENT OF LIVER FIBROSIS IN OBESE ADOLESCENTS.

Objective: The aim: To study the relationship between zonulin level and PNFI (pediatric non-alcoholic fatty liver disease fibrosis index) in obese adolescents.

Patients And Methods: Material and methods: A total of fifty-nine obese subjects aged 12-17 years and thirteen healthy subjects were included in the study. Clinical, biochemical parameters, including serum zonulin, were examined and abdominal ultrasound examination was performed.

[The pathogenetic aspects of the hyaluronidase activity of Proteus mirabilis].

The hyaluronidase activity of 83 P. mirabilis strains has been studied. The strains isolated from patients with chronic urologic infection possess the highest hyaluronidase activity, while the activity of strains isolated in cases of enteric disturbances and from purulent wound exudate has proved to be considerably lower, the difference between the latter being statistically insignificant.