Publications by authors named "L M PATRICK"

Marginalized groups in Manitoba, Canada, especially females and people who inject drugs, are overrepresented in new HIV diagnoses and disproportionately affected by HIV and structural disadvantages. Informed by syndemic theory, our aim was to understand people living with HIV's (PLHIV) gendered and intersecting barriers and facilitators across the cascade of HIV care before and during the COVID-19 pandemic. This study was co-designed and co-led alongside people with lived experience and a research advisory committee.

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  • A study surveyed 253 individuals, including autistic adults, parents, and professionals from Australia and New Zealand, to understand opinions on support services for young autistic children.
  • About half of the respondents thought support services were acceptable, while the other half felt it depended on the nature of the service provided.
  • Three main ideas emerged: prioritize children’s experiences, avoid "fixing" the child while respecting their unique perspectives, and recognize that personalized early support can significantly benefit autistic children.
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  • Enteric glia are important cells in the gut that help maintain various functions like motor control, tissue health, and immune responses, communicating closely with nerve cells under normal conditions.
  • When inflammation occurs, these glial cells become reactive, aiding in immune responses by releasing signaling molecules that attract immune cells, which can influence disease outcomes.
  • Recent research highlights the complex interactions between reactive enteric glia and immune cells during both acute conditions like postoperative inflammation and chronic issues such as inflammatory bowel diseases, pointing to the need for more studies on their role in gut inflammation.
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Microplastics and nanoplastics are pervasive in the environment and pollute every tissue in the body. Emerging research demonstrates a positive correlation between tissue concentrations of microplastics and several common diseases. The sources of exposure are well understood and can be controlled.

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Introduction: The use of volatile anaesthetic agents for the sedation of patients requiring critical care treatment offers several theoretical advantages over intravenous sedation, which may be of benefit in neurocritical care. However, there are concerns that they may increase intracranial pressure. The objective of this systematic review is to assess whether, and if so, to what extent volatile anaesthetic agents affect intracranial pressure, cerebral blood flow (CBF), cerebral oximetry and cerebrovascular autoregulation.

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